JCR-Role of SNPs in determining QTLs for major traits in cotton

MAJEED Sajid, RANA Iqrar Ahmad, ATIF Rana Muhammad, ALI Zulfiqar, HINZE Lori and AZHAR Muhammad Tehseen

摘要：单核苷酸多态性(SNP)是生物个体间最简单的遗传变异形式，可引起表型、生理生化特征的微小变化。这种多态性会引起各种突变，从而改变基因序列，可导致氨基酸出现明显的变化。已经开发了几种测定方法来鉴定和验证这些标记物，每种方法各有其优缺点，但通过测序进行基因分型是最常见、应用最广泛的方法。这些标记还与棉花的产量、纤维品质、铃重和基因对生物和非生物的胁迫反应等几个目标性状有关。产量相关性状的变化是植物育种家感兴趣的问题。利用这些标记，已经在棉花中鉴定出许多具有新功能的数量性状基因位点。这些信息可以通过分子育种方法用于作物改良。本文综述了这些标记物的鉴定及其对棉花重要经济性状基因功能的影响。

关键词：非生物胁迫；生物胁迫；棉花；早熟性；基于测序的基因分型

Abstract:

A single nucleotide polymorphism is the simplest form of genetic variation among individuals and can induce minor changes in phenotypic, physiological and biochemical characteristics. This polymorphism induces various mutations that alter the sequence of a gene which can lead to observed changes in amino acids. Several assays have been developed for identification and validation of these markers. Each method has its own advantages and disadvantages but genotyping by sequencing is the most common and most widely used assay. These markers are also associated with several desirable traits like yield, fibre quality, boll size and genes respond to biotic and abiotic stresses in cotton. Changes in yield related traits are of interest to plant breeders. Numerous quantitative trait loci with novel functions have been identified in cotton by using these markers. This information can be used for crop improvement through molecular breeding approaches. In this review, we discuss the identification of these markers and their effects on gene function of economically important traits in cotton.

Keywords:

Abiotic stresses; Biotic stresses; Cotton; Earliness; Genotyping by sequencing

Journal of Cotton Research. 2019; 2:5

https://doi.org/10.1186/s42397-019-0022-5

https://jcottonres.biomedcentral.com/articles/10.1186/s42397-019-0022-5